How legit is this? We turned to Whitney Bowe, M.D., a New York City-based dermatologist, to get the scoop. Turns out that melatonin is made not just in your brain, but in certain skin cells as well—making the skin a site of melatonin production and activity, Bowe says. “Melatonin is able to suppress UV-induced damage to skin cells and works as an antioxidant, meaning it protects cellular DNA from free-radical damage,” Bowe says. Considering that sun damage is the main cause of signs of aging (like wrinkles, fine lines, and dark spots), melatonin sounds like a pretty impressive wrinkle fighter.